Focal Articular Defects Modify Cartilage Contact Mechanics
نویسندگان
چکیده
منابع مشابه
Focal Articular Cartilage Defects of the Knee: Current Review
Injuries to the articular cartilage of the knee are common, they have a significant role in degenerative joint diseases, cartilage is unable to regenerate due to its inherent lack of vascular supply. The management of symptomatic focal traumatic articular cartilage lesions of the knee in active individuals remains a substantial challenge. Although many treatment options are currently available,...
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Autologous chondrocyte implantation (ACI) is the most widely used cell-based surgical procedure for the repair of articular cartilage defects. Challenges to successful ACI outcomes include limitation in defect size and geometry as well as inefficient cell retention. Second-generation ACI procedures have thus focused on developing three-dimensional constructs using native and synthetic biomateri...
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UNLABELLED We asked whether autologous chondrocyte implantation or osteochondral autograft transfer yields better clinical outcomes compared with one another or with traditional abrasive techniques for treatment of isolated articular cartilage defects and whether lesion size influences this clinical outcome. We performed a literature search and identified five randomized, controlled trials and ...
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The mechanics of contacting cartilage layers is fundamentally important to understanding the development, homeostasis and pathology of diarthrodial joints. Because of the highly nonlinear nature of both the materials and the contact problem itself, numerical methods such as the finite element method are typically incorporated to obtain solutions. Over the course of five decades, we have moved f...
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Full thickness osteochondral defects 6 mm in diameter were created in the weight-bearing regions of the femoral condyles in 5 adult mongrel dogs to study the contact pressure changes accompanying healing. A digital imaging technique employing Fuji Prescale film mapped contact pressures following 11 months of healing for comparison with contralateral normal knees, and knees with freshly made def...
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ژورنال
عنوان ژورنال: Molecular & Cellular Biomechanics
سال: 2006
ISSN: 1556-5300
DOI: 10.32604/mcb.2006.003.199